https://nova.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 Rhinovirus structure, replication, and classification https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:49281 Enterovirus genus in the family Picornaviridae. Different RVs bind to one of three known cellular receptors (intercellular adhesion molecule-1, low density lipoprotein receptor, and cadherin-related family member 3) on airway epithelial cells to initiate their replication cycle. Strategies to categorize RVs have been shaped by increased understanding of virus biology and have passed through several iterations since virus discovery in the 1950s. The RVs are currently classified into over 160 types within three species (A, B, and C) based on phylogenetic sequence criteria and distinct genomic features. An understanding of RV structure, replication, and diversity is necessary to develop novel treatment strategies. This chapter will provide an overview of the structural and genetic features that distinguish RV species, as well as methods of RV classification.]]> Tue 14 Nov 2023 14:44:32 AEDT ]]> Emerging therapeutic approaches https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:44421 Thu 13 Oct 2022 09:37:29 AEDT ]]> The interplay of the host, virus, and the environment https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:49260 Mon 08 May 2023 11:03:18 AEST ]]> In vivo experimental models of infection and disease https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:40023 Mon 04 Jul 2022 09:22:32 AEST ]]>